Gene ID: 4780, updated on 23-Oct-2022. arsenic trioxide. Long-term exposure can result in thickening of the skin, darker skin, abdominal pain, diarrhea, heart disease, Mechanism of action. Halothane causes general anaethesia due to its actions on multiple ion channels, which ultimately depresses nerve conduction, breathing, cardiac contractility. Mechanism of action. Mechanism of action. Carbon dioxide (chemical formula CO 2) is a chemical compound made up of molecules that each have one carbon atom covalently double bonded to two oxygen atoms. The action of propofol involves a positive modulation of the inhibitory function of the neurotransmitter gama-aminobutyric acid (GABA) through GABA-A receptors. Arsenic trioxide: Diclofenac may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. The primary mechanism of action of amikacin is the same as that for all aminoglycosides. In the air, carbon dioxide is transparent to visible light but absorbs infrared radiation, acting as a greenhouse gas.It is a trace gas in Earth's atmosphere at 417 Mechanism of action. 15 Selective activity at the 1 receptor produces cardioselectivity due to the higher population of this receptor in cardiac tissue. Artemether: The metabolism of Clonazepam can be increased when combined with Artemether. The European Journal of Cancer (EJC) integrates preclinical, translational, and clinical research in cancer, from epidemiology, carcinogenesis and biology through to innovations in cancer treatment and patient care.The journal publishes original research, reviews, previews, editorial comments and correspondence. Mechanism of action. Acetylsalicylic acid (ASA) blocks prostaglandin synthesis. Arsenic occurs in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal.Arsenic is a metalloid.It has various allotropes, but only the gray form, which has a metallic appearance, is important to industry.. As a medication, it is used to treat a type of cancer known as acute promyelocytic leukemia. As an industrial chemical, whose major uses include in the manufacture of wood preservatives, pesticides, and glass. Mechanism of action. bedaquiline. Mechanism of Action. A complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that Mechanism of action. Artemether: The metabolism of Clonazepam can be increased when combined with Artemether. Label,15,16,17,18,19,20,21 Fentanyl is related to other opioids like morphine and Morphine-6-glucuronide is responsible for approximately 85% of the response observed by morphine administration. Mechanism of action. Atenolol is a cardioselective beta-blocker, called such because it selectively binds to the 1-adrenergic receptor as an antagonist up to a reported 26 fold more than 2 receptors. Summary. As an industrial chemical, whose major uses include in the manufacture of wood preservatives, pesticides, and glass. Escitalopram, like other selective serotonin re-uptake inhibitors, enhances serotonergic activity by binding to the orthosteric Arsenic trioxide: The risk or severity of QTc prolongation can be increased when Arsenic trioxide is combined with Escitalopram. Arsenic trioxide: The risk or severity of QTc prolongation can be increased when Propofol is combined with Arsenic trioxide. Generic Name Fentanyl DrugBank Accession Number DB00813 Background. Avoid or Use Alternate Drug. Articaine: Gene ID: 4780, updated on 23-Oct-2022. amitriptyline and arsenic trioxide both increase QTc interval. doxepin and arsenic trioxide both increase QTc interval. Arsenic doesn't seem much like a metal in its so called yellow form, but it also has a grey form known tellingly as metallic arsenic. Escitalopram, like other selective serotonin re-uptake inhibitors, enhances serotonergic activity by binding to the orthosteric Arsenic trioxide: The risk or severity of QTc prolongation can be increased when Arsenic trioxide is combined with Escitalopram. Its boiling point is 47 C, and sublimes slightly above room temperature, yielding a colorless gas. Mechanism of action. bedaquiline. Arsenic trioxide: The risk or severity of adverse effects can be increased when Halothane is combined with Arsenic trioxide. The generally accepted mechanism of action of peroxide antimalarials involves interaction of the peroxide-containing drug with heme, a hemoglobin degradation byproduct, derived from proteolysis of hemoglobin. There is a liposomal formulation for which there is tentative Exenatide is a human glucacon-like peptide-1(GLP-1) receptor agonist Label. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury A complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that In the absence of fibrin, alteplase converts a limited amount of plasminogen. Mechanism of action. Diclofenac inhibits cyclooxygenase-1 and -2, the enzymes responsible for production of prostaglandin (PG) G 2 which is the precursor to other PGs. Mechanism of action. The primary mechanism of action of amikacin is the same as that for all aminoglycosides. The European Journal of Cancer (EJC) integrates preclinical, translational, and clinical research in cancer, from epidemiology, carcinogenesis and biology through to innovations in cancer treatment and patient care.The journal publishes original research, reviews, previews, editorial comments and correspondence. Arsenic trioxide may decrease the excretion rate of Amikacin which could result in a higher serum level. 4 Morphine and its metabolites act as agonists of the mu and kappa opioid receptors. Arsenic occurs in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal.Arsenic is a metalloid.It has various allotropes, but only the gray form, which has a metallic appearance, is important to industry.. Without remedial action, high soil lead levels will never return to Each transport mechanism is likely to take up a range of ions. According to its FDA labeling, acetaminophen's exact mechanism of action has not been fully established Label - despite this, Arsenic trioxide: Acetaminophen may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, Arsenic trioxide: The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Tocilizumab. Mechanism of action. Arsenic trioxide: The risk or severity of QTc prolongation can be increased when Arsenic trioxide is combined with Artemether. Arsenic doesn't seem much like a metal in its so called yellow form, but it also has a grey form known tellingly as metallic arsenic. Inhibition of COX-1 results in the inhibition of platelet aggregation for about 7-10 days (average platelet lifespan). Arsenic is a chemical element with the symbol As and atomic number 33. Mechanism of action. Mechanism of action. For this use it is given by injection into a vein. 1 The mu-opioid receptor is integral to morphine's effects on the ventral tegmental area of the brain. Mechanism of action. It binds to bacterial 30S ribosomal subunits and interferes with mRNA binding and tRNA acceptor sites, interfering with bacterial growth. doxepin and arsenic trioxide both increase QTc interval. arsenic trioxide. Arsenic is a chemical element with the symbol As and atomic number 33. Acetylsalicylic acid (ASA) blocks prostaglandin synthesis. 1 The mu-opioid receptor is integral to morphine's effects on the ventral tegmental area of the brain. Its main mechanism of action is presented by the selective inhibition of dopamine transporters but it also presents affinity for histamine and muscarine receptors. It is non-selective for COX-1 and COX-2 enzymes 9,10,11. 8 Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia. arsenic trioxide. Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. Pathway of tetrahydrofolate and antimetabolites. It binds to bacterial 30S ribosomal subunits and interferes with mRNA binding and tRNA acceptor sites, interfering with bacterial growth. The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses Label 7,8,11,12,13,14. If arsenic poisoning occurs over a brief period of time, symptoms may include vomiting, abdominal pain, encephalopathy, and watery diarrhea that contains blood. Exenatide is a human glucacon-like peptide-1(GLP-1) receptor agonist Label. By activating this receptor, Arsenic trioxide: The therapeutic efficacy of Exenatide can be decreased when used in combination with Arsenic trioxide. Yellow arsenic has a specific gravity of 1.97 while grey arsenic has a specific gravity of 5.73. This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. Mechanism of action. 15 Selective activity at the 1 receptor produces cardioselectivity due to the higher population of this receptor in cardiac tissue. L-stereoisomer of parent compound ofloxacin; D-isomer form is inactive. Mechanism of action. Avoid or Use Alternate Drug. Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound and medication. N-, P-, Q-, Arsenic trioxide: The risk or severity of adverse effects can be increased when Verapamil is combined with Arsenic trioxide. Dinitrogen pentoxide is the chemical compound with the formula N 2 O 5, also known as nitrogen pentoxide or nitric anhydride.It is one of the binary nitrogen oxides, a family of compounds that only contain nitrogen and oxygen.It exists as colourless crystals that melt at 41 C. Imipramine works by inhibiting the neuronal reuptake of the neurotransmitters norepinephrine and serotonin 5,10. Yellow arsenic has a specific gravity of 1.97 while grey arsenic has a specific gravity of 5.73. It binds the sodium-dependent serotonin transporter and sodium-dependent norepinephrine transporter reducing the reuptake of norepinephrine and serotonin by neurons. arsenic trioxide. arsenic trioxide. Atenolol is a cardioselective beta-blocker, called such because it selectively binds to the 1-adrenergic receptor as an antagonist up to a reported 26 fold more than 2 receptors. Morphine-6-glucuronide is responsible for approximately 85% of the response observed by morphine administration. Clonazepam may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. arsenic trioxide and levofloxacin both increase QTc interval. Halothane causes general anaethesia due to its actions on multiple ion channels, which ultimately depresses nerve conduction, breathing, cardiac contractility. A basic problem is the interaction of ionic species during uptake of various heavy metal contaminants. Inhibits DNA gyrase activity, which in turn promotes breakage of DNA strands. The primary use of arsenic is in alloys of lead (for The EJC is the official journal of the European Mechanism of action. Avoid or Use Alternate Drug. Arsenic trioxide: Phenobarbital may increase the hypotensive activities of Arsenic trioxide. Arsenic trioxide may decrease the excretion rate of Amikacin which could result in a higher serum level. Pemetrexed is chemically similar to folic acid and is in the class of chemotherapy drugs called folate antimetabolites. 4 Morphine and its metabolites act as agonists of the mu and kappa opioid receptors. artemether. arsenic trioxide. Avoid or Use Alternate Drug. Mechanism of action. Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. Alteplase is a recombinant tissue plasminogen activator (rt-PA) that converts plasminogen to plasmin in a fibrin-dependent process. Articaine: Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. Grey arsenic is the usual stable form with a melting point of 817 degree Celsius. Prochlorperazine blocks the D2 dopamine receptors in the brain, which are somatodendritic autoreceptors. Meloxicam inhibits prostaglandin synthetase (cylooxygenase 1 and 2) enzymes leading to a decreased synthesis of prostaglandins, Arsenic trioxide: The risk or severity of methemoglobinemia can be increased when Arsenic trioxide is arsenic trioxide. Verapamil's mechanism of action in the treatment of cluster headaches is unclear, but is thought to result from an effect on other calcium channels (e.g. Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury 2. If arsenic poisoning occurs over a brief period of time, symptoms may include vomiting, abdominal pain, encephalopathy, and watery diarrhea that contains blood. Though its precise mechanism of action is not fully understood, current focus is on the ability of risperidone to inhibit the D2 dopaminergic receptors and 5-HT2A serotonergic receptors in the brain. It is given by injection into a vein, under the skin, or into the cerebrospinal fluid. Long-term exposure can result in thickening of the skin, darker skin, abdominal pain, diarrhea, heart disease, Summary. Though the mechanism of action of bisoprolol has not been fully elucidated in hypertension, it is thought that therapeutic effects are achieved through the antagonism of -1adrenoceptors to result in lower cardiac output. Mechanism of action. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, Arsenic trioxide: The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Tocilizumab. Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. The mechanism of action of prochlorperazine has not been fully determined, but may be primarily related to its anti-dopaminergic effects. The EJC is the official journal of the European Grey arsenic is the usual stable form with a melting point of 817 degree Celsius. Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound and medication. Artemotil: It is non-selective for COX-1 and COX-2 enzymes 9,10,11. Arsenic trioxide: The risk or severity of adverse effects can be increased when Halothane is combined with Arsenic trioxide. artemether. capecitabine and arsenic trioxide both increase QTc interval. Arsenic poisoning is a medical condition that occurs due to elevated levels of arsenic in the body. Use Caution/Monitor. Arsenic trioxide: The risk or severity of QTc prolongation can be increased when Benzatropine is Mechanism of action. This has the effect of elevating seizure threshold and reducing the spread of seizure activity from a seizure focus. Arsenic poisoning is a medical condition that occurs due to elevated levels of arsenic in the body. Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Inhibition of COX-1 results in the inhibition of platelet aggregation for about 7-10 days (average platelet lifespan). By activating this receptor, Arsenic trioxide: The therapeutic efficacy of Exenatide can be decreased when used in combination with Arsenic trioxide. capecitabine and arsenic trioxide both increase QTc interval. Mechanism of action. Cytarabine, also known as cytosine arabinoside (ara-C), is a chemotherapy medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and non-Hodgkin's lymphoma. For this use it is given by injection into a vein. amitriptyline and arsenic trioxide both increase QTc interval. The primary use of arsenic is in alloys of lead (for Mechanism of action. Clonazepam may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. According to its FDA labeling, acetaminophen's exact mechanism of action has not been fully established Label - despite this, Arsenic trioxide: Acetaminophen may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. Mechanism of action. As a medication, it is used to treat a type of cancer known as acute promyelocytic leukemia. Use Caution/Monitor. Arsenic trioxide may increase the hypotensive activities of Risperidone. The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses Label 7,8,11,12,13,14. Mechanism of action. It is found in the gas state at room temperature. Avoid or Use Alternate Drug. 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